Psoriatic Arthritis Associated with Vestibular and Hearing Disorders

Posted by Kerrie Denner

By Michael R. Page, PharmD, RPh | September 10, 2014

Psoriatic arthritis may be difficult to distinguish from other types of arthritis. According to results of a new study, assessing a patient’s sense of balance and hearing ability may be an aid in the diagnosis.  

Psoriatic arthritis is a chronic, inflammatory rheumatic disease that is difficult to distinguish from rheumatoid arthritis. However, one of the hallmarks of psoriatic arthritis is the constellation of vestibular impairment abnormalities associated with the condition.  

On September 1, researchers Amor-Dorado et al published a study in The Journal of Rheumatology evaluating the relationship between impaired balance, vertigo, and other audiovestibular manifestations of psoriatic arthritis.  

In a series of 60 patients that met diagnostic criteria for psoriatic arthritis and 60 matched control patients, investigators assessed patients using an audiogram and a validated assessment of balance known as computerized dynamic posturography. To exclude patients with potential causes outside of psoriatic arthritis, investigators excluded patients with cardiovascular disease, cerebrovascular complications, peripheral artery disease, renal insufficiency, syphilis, Meniere disease, and users of potentially ototoxic medications.  

Of the 60 patients with psoriatic arthritis, more than half (60%) showed signs of hearing loss on an audiogram versus 8.3% of matched controls (P<.001). In addition, nearly one-fourth (23%) of patients with psoriatic arthritis showed signs of difficulty balancing, compared with 0% of control patients (P<.001).    

The disease process of psoriatic arthritis may cause inner ear damage that may harm patients' ability to maintain balance and normal hearing. Because psoriatic arthritis is often difficult to distinguish from rheumatoid arthritis, vestibular symptoms may be 1 way to aid in distinguishing these 2 separate conditions. With the availability of treatments such as apremilast that target the disease process of psoriatic arthritis, the distinction between rheumatoid arthritis and psoriatic arthritis is more relevant than ever. 

Source: HCP Live


Accessed 9/10/2014

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