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News Updates: Research

Concussion increases risk for vision problems

Posted by Kerrie Denner

SAN DIEGO — Nearly 70% of children diagnosed with concussion had at least one vision problem, according to data presented here.

Christina L. Master, MD, of the Children’s Hospital of Philadelphia in Philadelphia, and colleagues assessed visual symptoms, visual acuity, eye alignment, near point of convergence, vergence amplitude/facility, accommodative amplitude/facility and saccadic eye movement speed and accuracy among 100 children diagnosed with concussion. Study participants had a mean age of 14.5 years.

Otonomy Enrolls First Meniere's Disease Patients in OTO-104 Multiple-Dose Safety Study

Posted by Kerrie Denner

Otonomy, Inc. (Nasdaq:OTIC), a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapeutics for diseases and disorders of the inner and middle ear, today announced the enrollment of the first patients in a multiple-dose safety study of OTO-104 initiated in the United Kingdom (U.K.) in patients with Ménière's disease.

Researchers explore gene expression in normal vestibular nerves, vestibular schwannomas

Posted by Kerrie Denner

Researchers from the University of Toronto, directed by Drs. Gelareh Zadeh and Boris Krischek, investigated gene expression in normal vestibular nerves and vestibular schwannomas (VSs). Two important discoveries were made: 1) there is negligible difference between VSs that sporadically occur and those commonly associated with neurofibromatosis Type 2 (NF2), a genetic disorder; and 2) the overexpressed PI3K/AKT/mTOR signaling pathway in these tumors may be an excellent therapeutic target.

New Treatment Successful for Rare and Disabling Movement Disorder, the Mal de Debarquement Syndrome (MdDS)

Posted by Kerrie Denner

People who suffer from a rare illness, the Mal de Debarquement Syndrome (MdDS), now have a chance for full recovery thanks to treatment developed by researchers at the Icahn School of Medicine at Mount Sinai.  Their findings were published online in the July issue of Frontiers in Neurology.  

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