News Updates: Research

Poor Balance Tied to Small-Vessel Disease, Cognitive Decline

Posted by Cynthia Ryan

The inability to stand on one leg for more than 20 seconds is significantly associated with cerebral small-vessel disease (cSVD), specifically lacunar infarctions and micro-bleeds, in healthy patients, results of a new study suggest.

Such postural instability was also linked to cognitive decline in the middle-aged to elderly patients included in the study.

Seasonality of Benign Paroxysmal Positional Vertigo

Posted by Kerrie Denner

By Jeannette Wick | November 30, 2014

Benign paroxysmal positional vertigo (BPPV), an idiopathic condition for patients, occurs when otoconia of the utricular macula become dislodged and floating debris moves into semicircular canals.

Recently, researchers have noted patients with BPPV tend to have low serum vitamin D levels compared with controls. BPPV sufferers develop osteoporosis more often than people who do not have BPPV. BPPV also recurs more frequently in patients with osteoporosis compared with those with normal bone mineral density.

Otonomy obtains rights to data to support development of a treatment for tinnitus

Posted by Kerrie Denner

Otonomy, Inc. (Nasdaq: OTIC), a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapeutics for diseases and disorders of the inner and middle ear, and Ipsen (Euronext: IPN; ADR: IPSEY), a global specialty-driven pharmaceutical company, today announced that they have entered into an exclusive licensing agreement enabling Otonomy to utilize Ipsen's gacyclidine data in the development and registration of OTO-311.

Detection of Autoimmune Reactions and Diagnostic Biomarker Candidates in Meniere's

Posted by Kerrie Denner


Meniere's disease is an inner ear disorder that can manifest as fluctuating vertigo, sensorineural hearing loss, tinnitus, and aural fullness. However, the pathologic mechanism of Meniere's disease is still unclear. In this study, we evaluated autoimmunity as a potential cause of Meniere's disease.


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